uniqname: Facility Core Use

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EXCLUDE ID from the spreadsheetEXCLUDE Timestamp from the spreadsheetEXCLUDE Uniqname from the spreadsheetEXCLUDE PI Uniqname from the spreadsheetEXCLUDE PI Name First from the spreadsheetEXCLUDE PI Name Middle from the spreadsheetEXCLUDE PI Name Last from the spreadsheetEXCLUDE PI Email from the spreadsheetEXCLUDE PI Phone from the spreadsheetEXCLUDE PI Affiliation from the spreadsheetEXCLUDE PI Title from the spreadsheetEXCLUDE PI PostalAddress from the spreadsheetEXCLUDE Investigator Membership from the spreadsheetEXCLUDE Project Grant Cycle from the spreadsheetEXCLUDE Project Cost from the spreadsheetEXCLUDE Project Description from the spreadsheetEXCLUDE Project Cores from the spreadsheetEXCLUDE Project Cores Shortcode from the spreadsheetEXCLUDE Project Cores EAC from the spreadsheetEXCLUDE Project Cores OBIC from the spreadsheetEXCLUDE Project Cores IHSC from the spreadsheetEXCLUDE Project Assay from the spreadsheetEXCLUDE Research Administrator Name Display from the spreadsheetEXCLUDE Research Administrator Uniqname from the spreadsheetEXCLUDE Contact Name Display from the spreadsheetEXCLUDE Contact Email from the spreadsheetEXCLUDE Contact Phone from the spreadsheetEXCLUDE Project Cost Billing Date from the spreadsheetEXCLUDE Acknowledgement from the spreadsheet

Table for Subsidy Request Applications

Array ( [ID] => ID [Timestamp] => Timestamp [Uniqname] => Uniqname [PI_Uniqname] => PI_Uniqname [PI_Name_First] => PI_Name_First [PI_Name_Middle] => PI_Name_Middle [PI_Name_Last] => PI_Name_Last [PI_Email] => PI_Email [PI_Phone] => PI_Phone [PI_Affiliation] => PI_Affiliation [PI_Title] => PI_Title [PI_PostalAddress] => PI_PostalAddress [Investigator_Membership] => Investigator_Membership [Project_Grant_Cycle] => Project_Grant_Cycle [Project_Cost] => Project_Cost [Project_Description] => Project_Description [Project_Cores] => Project_Cores [Project_Cores_Shortcode] => Project_Cores_Shortcode [Project_Cores_EAC] => Project_Cores_EAC [Project_Cores_OBIC] => Project_Cores_OBIC [Project_Cores_IHSC] => Project_Cores_IHSC [Project_Assay] => Project_Assay [Research_Administrator_Name_Display] => Research_Administrator_Name_Display [Research_Administrator_Uniqname] => Research_Administrator_Uniqname [Contact_Name_Display] => Contact_Name_Display [Contact_Email] => Contact_Email [Contact_Phone] => Contact_Phone [Project_Cost_Billing_Date] => Project_Cost_Billing_Date [Acknowledgement] => Acknowledgement )
IDTimestampUniqnamePI UniqnamePI Name FirstPI Name MiddlePI Name LastPI EmailPI PhonePI AffiliationPI TitlePI PostalAddressInvestigator MembershipProject Grant CycleProject CostProject DescriptionProject CoresProject Cores ShortcodeProject Cores EACProject Cores OBICProject Cores IHSCProject AssayResearch Administrator Name DisplayResearch Administrator UniqnameContact Name DisplayContact EmailContact PhoneProject Cost Billing DateAcknowledgement
292019-01-20 17:07:10rlcRitaLoch-Carusorlc@umich.edu734-936-1256Environmental Health Sciences - Faculty and Staff School of Public Health - Faculty and Staff Program in the Environment - Faculty and Staff School for Environ and Sustain - Faculty and Staff Professor of Toxicology, Department of Environmental Health Sciences, School of Public Health and Professor of Program in the Environment, School for Environment and Sustainability Environmental Hlth Sci M6108 SPH2, 1415 Washington Hts. Ann Arbor MI 48109-2029Yes2017-2018$1400Diethylhexyl phthalate (DEHP) is an environmental toxicant linked to preterm birth and preeclampsia. However, the specific mechanisms of by which these compounds contribute to these adverse birth outcomes is still unclear. The proposed work will use metabolomics to measure changes in hormones and eicosanoids in the blood of pregnant rats in order to gain insight into circulating markers of DEHP exposure and the mechanisms by which exposure might lead to adverse pregnancy outcomes. Our lab has generated serum samples from pregnant rats treated with DEHP at multiple doses (0, 1, 10 or 100mg/kg/day from gestational days 12-16, IACUC #PRO00006721). We are requesting a subsidy in order to partially cover the costs of this analysis using the Michigan Regional Comprehensive Metabolomics Resource Core. This work addresses the mission of M-LEEAD by providing new information on the contribution of an environmental contaminant to the etiology of adverse pregnancy outcomes. a:1:{i:0;s:12:"Metabolomics";}Targeted metabolomics analysis for hormones and prostanoids in blood serum samples from pregnant rats. Faith Bjorkfbjork@umich.edu936-1826Feb 28 2019Yes
282019-01-18 14:40:44ddolinoyDanaDolinoyddolinoy@umich.edu734-647-3155Environmental Health Sciences - Faculty and Staff School of Public Health - Faculty and Staff Nutritional Sciences - Faculty and Staff NSF International Department Chair of Environmental Health Sciences, Chair, Department of Environmental Health Sciences, Professor of Environmental Health Sciences and Professor of Nutritional Sciences, School of Public Health. Environmental Health Sciences 6667 SPH I/1415 Washington Heights Ann Arbor MI 48109-2029Yes2017-20181400Early life exposure to environmental toxicants can have an adverse effect on later life health in both humans and animals. Epigenetic mechanisms, such as DNA methylation, can be used as potential biomarkers of disease states and environmental exposures. Utilizing an established mouse model of perinatal exposures to human-relevant doses of Lead and DEHP, the goal of the project is to evaluate tissue and cell specific epigenetic alterations associated with these perinatal exposures and later health outcomes. a:1:{i:0;s:11:"Epigenomics";}Enhanced Reduced Representation Bisulfite Sequencing (ERRBS) will be performed by the University of Michigan Epigenomics Core on DNA samples isolated from multiple different tissues of mice perinatally exposed to either lead, DEHP, or control conditions. Genome-wide methylation profiles will be analyzed for correlation with these toxicant exposures. Tamara Jonestrmeier@umich.edu734-764-6213March 1, 2019Yes
272018-09-19 14:44:00meekerjJohnMeekermeekerj@umich.edu734-764-7184Environmental Health Sciences - Faculty and Staff School of Public Health - Faculty and Staff Sch of Public Hlth-Dean's Ofc - Faculty and Staff HITS OCIO Administration - Sponsored Affiliate Professor of Environmental Health Sciences and Senior Associate Dean for Research, School of Public Health Environmental Hlth Science M6226 SPH II 2029Yes2017-2018$1400 Preterm birth is the leading cause of infant mortality worldwide, and also greatly increases the risk of developing serious health complications in childhood and throughout life. Conditions that contribute to preterm birth remain largely unclear, though an influence by environmental exposures is suspected but poorly understood. In our preliminary work, we found that exposure to common chemicals, such as phthalates and bisphenol A (BPA), may contribute to this serious but understudied public health problem. We also observed strong associations between phthalates/BPA and general markers of oxidative stress, and in turn between these general markers of oxidative stress and risk of preterm birth. In this nested case-control study within an ongoing cohort of pregnant women in Puerto Rico (PROTECT), we will explore untargeted lipidomics, as well as levels of eicosanoids specific to arachidonic acid oxidation pathways, in relation to both environmental exposures and preterm birth.a:1:{i:0;s:12:"Metabolomics";}Two assays will be performed. Untargeted Metabolomics and Shotgun LipidomicsJennifer Fernandezjafernan@umich.edu734-763-0656Already billedYes
262018-09-13 14:40:09gaydojacJaclynMichelleGoodrichgaydojac@umich.edu734-647-4564Environmental Health Sciences, School of Public HealthResearch Assistant Professor 1415 Washington Heights Environmental Health Sciences Ann Arbor MI 48109-2029Yes2017-20181400Environmental exposures may perturb epigenetic programming during key developmental periods including early gestation, thereby setting the stage for adverse birth outcomes and disease development later in life. Discovering the exposures and their potential mechanisms (e.g., epigenetics) underlying this risk is in line with the mission of the M-LEEaD. In this project, we will utilize samples from the Michigan Mother Infant Pairs (MMIP) birth cohort. The overall objectives for the study are to identify toxicants that influence birth outcomes and to examine whether DNA methylation is altered by these exposures, serving as a potential mechanism of toxicity. While exposure assessment and preliminary epigenetic measures are complete, we are now submitting an additional 64 cord blood leukocyte samples for DNA methylation analysis via the MethylationEPIC to increase sample size and power to detect associations between exposures, differentially methylated genes, and birth outcomes. a:2:{i:0;s:11:"Epigenomics";i:1;s:4:"OBIC";}DNA Sequencing CoreDNA methylation analysis will be performed at the DNA Sequencing Core via the Infinium MethlationEPIC BeadChip (Illumina). This array quantifies methylation at >850,000 CpG sites throughout the human genome. DNA isolated from 64 umbilical cord blood leukocyte samples will be bisulfite converted and sent to the DNA Sequencing Core. There, it will be hybridized to the BeadChips and scanned. Raw image data will be returned to the investigators for processing and statistical analysis to address study objectives. Of note, this project involves a collaboration between M-LEEaD members Drs. Padmanabhan and Goodrich as well as Dr. Charles Burant. The analysis will be paid for by an account of Dr. Burantâ??s, but Dr. Goodrich is requesting for the P30 subsidy to be applied to this project that we are jointly working on.10/30/18Yes
252018-08-09 16:33:45lmyrantLaurieKathleenSvobodalmyrant@umich.edu734-764-2032Alumni Environmental Health Sciences - Faculty and Staff School of Public Health - Faculty and Staff HITS OCIO Administration - Sponsored Affiliate Research Assistant Professor, Environmental Health Sciences, School of Public Health SPH Environmental Health Sciences 1415 Washington Heights Ann Arbor MI 48109-2029Yes2017-2018$1400Cardiovascular diseases are a major cause of morbidity and mortality world-wide, and accumulating evidence suggests an important role for early-life toxicant exposures, including lead (Pb), in their etiology. As developmental Pb exposure remains a public health concern in both industrialized and developing nations, a better understanding of how Pb contributes to cardiovascular diseases is urgently needed. Despite known impacts of Pb exposure on heart function, the effects of Pb on the cardiac transcriptome and epigenome have not been investigated. the purpose of this proposal is to test the hypothesis that exposure to Pb in utero and during lactation leads to changes in the transcriptome of the heart, particularly in environmentally labile genes critical for normal cardiac development and physiology.a:2:{i:0;s:14:"Bioinformatics";i:1;s:11:"Epigenomics";}RNA-seq will be conducted on pulverized heart tissue from mice exposed to Pb or control conditions during gestation and lactation. To assess the contribution of age and sex to the effects of Pb on the cardiac transcriptome, male and female mice will be evaluated at two time points. Tissue cryo pulverization and aliquotting will be conducted by the Epigenomics Core. Estimated cost for this service is approximately $1000 (estimate provided by Dr. Claudia Lalancette). QC analysis, alignment to the mouse reference genome, and differential expression testing, and gene set enrichment analysis will be conducted with the assistance of the M-LEEaD Omics and BioInformatics Core. 11/8/18Yes
242018-08-06 10:45:59wylieRobinWyliewylie@umich.edu734-615-9575Epidemiology Department - Faculty and Staff School of Public Health - Faculty and Staff Web Designer/Administrative Intermediate Epidemiology 6638 SPH I Ann Arbor MI 48109-2029Yes2017-2018999Project_Descriptiona:6:{i:0;s:14:"Bioinformatics";i:1;s:11:"Epigenomics";i:2;s:12:"Metabolomics";i:3;s:3:"EAC";i:4;s:4:"OBIC";i:5;s:4:"IHSC";}Project_Cores_EACProject_Cores_OBICProject_Cores_IHSCProject_AssayContact_Name_Displayexample@example.com1234567890Project_Cost_Billing_DateYes
232018-08-06 10:38:11wylieRobinPI_Name_MiddleWyliewylie@umich.edu734-615-9575Epidemiology Department - Faculty and Staff School of Public Health - Faculty and Staff Web Designer/Administrative Intermediate Epidemiology 6638 SPH I Ann Arbor MI 48109-2029Yes2017-2018999Project_Descriptiona:6:{i:0;s:14:"Bioinformatics";i:1;s:11:"Epigenomics";i:2;s:12:"Metabolomics";i:3;s:3:"EAC";i:4;s:4:"OBIC";i:5;s:4:"IHSC";}Project_Cores_EACProject_Cores_OBICProject_Cores_IHSCProject_AssayContact_Name_Displayexample@example.com1234567890Project_Cost_Billing_DateYes
222018-07-23 10:46:01wylieRobinWyliewylie@umich.edu734-615-9575Epidemiology Department - Faculty and Staff School of Public Health - Faculty and Staff Web Designer/Administrative Intermediate Epidemiology 6638 SPH I Ann Arbor MI 48109-2029Yes2017-2018999Ipsum lorem.a:2:{i:0;s:11:"Epigenomics";i:1;s:4:"OBIC";}Ipsum lorem.Ipsum lorem.Project_Cost_Billing_DateYes
212018-05-07 17:59:08rlcRitaPI_Name_MiddleLoch-Carusorlc@umich.edu734-936-1256Environmental Health Sciences - Faculty and Staff School of Public Health - Faculty and Staff LSA UG: Environment - Faculty and Staff College of Lit, Science & Arts - Faculty and Staff Professor of Toxicology, Department of Environmental Health Sciences, School of Public Health and Professor of Program in the Environment, College of Literature, Science, and the Arts and School of Environment and Sustainability Environmental Hlth Sci M6108 SPH2, 1415 Washington Hts. Ann Arbor MI 48109-2029No2017-20181400Project_Descriptiona:6:{i:0;s:14:"Bioinformatics";i:1;s:11:"Epigenomics";i:2;s:12:"Metabolomics";i:3;s:3:"EAC";i:4;s:4:"OBIC";i:5;s:4:"IHSC";}Project_Cores_EACProject_Cores_OBICProject_Cores_IHSCProject_AssayRobin Wyliewylie@umich.edu734-615-9575Project_Cost_Billing_DateYes
202018-05-03 17:14:32rlcRitaPI_Name_MiddleLoch-Carusorlc@umich.edu734-936-1256Environmental Health Sciences - Faculty and Staff School of Public Health - Faculty and Staff LSA UG: Environment - Faculty and Staff College of Lit, Science & Arts - Faculty and Staff Professor of Toxicology, Department of Environmental Health Sciences, School of Public Health and Professor of Program in the Environment, College of Literature, Science, and the Arts and School of Environment and Sustainability Environmental Hlth Sci M6108 SPH2, 1415 Washington Hts. Ann Arbor MI 48109-2029No2017-20181999Project_Descriptiona:3:{i:0;s:14:"Bioinformatics";i:1;s:11:"Epigenomics";i:2;s:12:"Metabolomics";}Project_AssayRobin Wyliewylie@umich.edu734-615-9575Project_Cost_Billing_DateYes