Pilot Project Funding

Funded Pilot Projects
If your pilot project appears below you can update your project here (intranet, for U-M personnel only).

May 2017

“Increasing Climate Resiliency in Detroit through the Co-Analysis of Survey Data”
PI: Larissa Larsen
“Placental Epigenomics for Environmental Health Research”
PI: Jaclyn Goodrich
“Health Risks to Vulnerable Populations from Exposures to Airborne Asbestos from the Demolition of Abandoned Homes in Detroit”
PI: Richard Neitzel

January 2017

“Alteration of epigenomic reprogramming of normal human breast stem cells by cadmium”
PI: Justin Colacino
Co-investigator: Lada Koneva
“Impact of exposome on maternal and fetal inflammasome”
PI: Vasantha Padmanabhan
Co-investigator: Charles Burant, MD, PhD Robert C. and Veronica Atkins Professor of Metabolism Professor of Internal Medicine (Metabolome) Jaclyn Goodrich, PhD Research Assistant Professor of Environmental Health Sciences Univ. of Michigan School of Public Health (epigenetics)
“Particulate Matter Induced DNA Methylomic Changes in Bronchial Epithelial Cells”
PI: Steven Huang
Co-investigator: Maureen Sartor Associate Professor of Computational Medicine and Bioinformatics, Medical School and Associate Professor of Biostatistics, School of Public Health Omics and Bioinformatics Core Lead and Collaborator
“Climate and cardiopulmonary health: Does excess weight enhance risk?”
PI: Patricia Koman
Co-investigator: 1) Ricardo de Majo, geospatial analyst, Health Behavior Health Education, acquire and analyze data 2) Dr. Marie O’Neill, Associate Professor, Epidemiology and Environmental Health Sciences, Integrated Health and Statistics Center Core services provider
“Understanding the combined effects of breastmilk PCB exposure and maternal metabolic disease on infant growth outcomes”
PI: Brigid Ellen Gregg
Co-investigator: Lindsay Ellsworth-Fellow in Neonataology, Department of Pediatrics Role: will be carrying out proposed sample extractions and analyses
“Evaluation of Placental Responses to Environmental Toxicants Using Metabolomic and Transcriptomic Approaches”
PI: Rita Loch-Caruso
Co-investigator: Sean Harris, Postdoctoral Fellow, Environmental Health Sciences Elana Elkin, Graduate Student, Environmental Health Sciences Anthony Su, Graduate Student, Environmental Health Sciences

January 2016

“External proficiency testing of heavy metal assessment for epidemiologic studies in the Study of Women’s Health Across the Nation (SWAN)”
PI: Sung Kyun Park
Co-investigator: Stuart Batterman
“Creating fine spatial resolution air pollution and temperature data for linking to Michigan birth outcomes”
PI: Marie O’Neill
Co-Investigators: Amy Schulz, Carina Gronlund, Veronica Berrocal, Ricardo de Majo
“Are sex differences in effects of early obesogen exposure on metabolic outcomes in adolescence mediated by genome-wide DNA methylation?”
PI: Karen Peterson
Co-Investigators: Jaclyn Goodrich, Wei Perng, Peter Song
“MI-Environment: Promoting climate-related health within Michigan’s vulnerable communities”
PI: Natalie Sampson
Co-investigator: Trish Koman
“Epigenetic modifications and altered gene expression induced by source-specific air born fine particles in human lung cells”
PI: Andrew Ault
Co-investigator: Ying-Hsuan Lin
“Measurements of PBDE Levels in a population-based sample of lupus patients and controls in Southeastern Michigan”
PI: Emily Somers
Co-investigators: Siobán D. Harlow, Stuart Batterman

January 2015

“In Vivo Monitoring of Toxicant-Induced Placental Aging in Mice”
Co-PIs: Rita Loch-Caruso, PhD; Steven Domino, MD, PhD Co-investigators: Kelly Hogan, PhD; Mark Chames, MD
“Transcriptional and Post-Transcriptional Effects of Mutations and Environmental Factors Associated with Autism”
PI: Mats Ljungman, PhD Co-investigator: Donna Martin, MD
“Addressing Public Health Issues within the Detroit Blight Elimination Program: Transforming Health Data into Action and Policy”
PI: Eden Wells, MD, MPH, FACPM Co-investigators: Regina Royan, Doug Strane
“Methylmercury and gene‐specific DNA methylation of CD4+ T cells in lupus”
PI: Emily Somers, PhD, ScM

January 2014

“The Influence of Prostaglandin E2 and Transforming Growth Factor-ß1 on DNA Methylation Patterns in Idiopathic Pulmonary Fibrosis”
PI: Steven Huang, PhD Co-investigator: Maureen Sartor, PhD
“Epigenetic Effects of Prenatal Environmental Exposures”
Co-PIs: Margit Burmeister, PhD; Betsy Lozoff, MD Co-investigators: Dana Dolinoy, PhD; John Meeker, PhD, Maureen Sartor, PhD; Peter Song, PhD; Jie Shao, MD
“A Pilot Study for Multiple Pollutant Exposures and Ovarian Aging”
PI: Sung Kyun Park, PhD Co-investigators: Sioban Harlow, PhD; Bhramar Mukherjee, PhD; Stuart Batterman, PhD
“Tissue Specific Epigenetic Alterations and Birth Outcomes Following Perinatal Bispehnol A (BPA) Exposure”
PI: Vasantha Padmanabhan; Co-investigator: Dana Dolinoy, PhD

November 2012

“Epigenetics and Mercury Exposure in the American Dental Association Cohort”
Co-PIs: Niladri Basu, PhD; Dana Dolinoy, PhD Co-investigator: Al Franzblau, PhD
“Mother and Child Environmental (Mace) Cohort – Epigenetic Changes Associated With Ambient Pollution”
PI: Stuart Batterman, PhD Co-investigator: P. Reddy, PhD; N. Naidoo, PhD
“The interplay of heavy metals and gut microbiome on epigenetic modification”
Co-PIs: Chuanwu Xi, PhD; Dana Dolinoy, PhD Co-investigator: Christopher Faulk, PhD; Jianfeng Wu, PhD
“Genome-wide DNA methylation changes in Behçet’s disease monocytes”
PI: Amr Sawalha, PhD

February 2012

“Prenatal Bisphenol-A Exposure and Overeating on Metabolic Homeostasis”
PI: Almudena Veiga-Lopez, DVM, PhD Co-investigator: Vasantha Padmanabhan, PhD
“The role of environmental toxicants in the dysregulation of microRNAs leading to amyotrophic lateral sclerosis”
Co-PIs: Raymond Yung, MB, ChB and Eva L. Feldman MD, PhD Co-Investigators: Brian Christopher Callaghan, MD; Claudia Figueroa-Romero, PhD; Junguk Hur, PhD
“Probing Trichloroethylene Embryotoxicity in the Mouse: Searching for Mechanistic Fidelity between Gene Expression and DNA Methylation using a Genome-Wide Expression and Tiling Array Approach”
Co-PIs: Dana Dolinoy, PhD and Craig Harris, PhD Co-Investigators: Bhramar Mukherjee, PhD; Jung Hei (Julie) Kim, PhD; Karilyn E. Sant, MPH
“Effect of in utero BPA exposure on allergen-induced pulmonary inflammation in adult mice”
PI: Peter Mancuso, PhD Co-Investigator: Edmund O’Brien, PhD
“In Utero Lead Exposure and Neuron-specific Epigenetic Change Associated with Life-Course Neurobehavioral Phenotypes”
PI: Dana Dolinoy, PhD Co-Investigators: Christopher Faulk, PhD; Howard Hu, MD, ScD; Karen E. Peterson, ScD; Brisa N. Sanchez, PhD